01.

Phase 01
Weight Loss Spray
Daily appetite support for the active loss phase — built to back the work you're putting in.
Save 15% with monthly auto-refill
Two sprays. One weight journey.
Oprimaze pairs a weight loss spray with a weight maintenance spray — a hemp-derived daily support tool built around the two phases that actually matter: getting there, and staying there.
Free shipping over $74.90 · 30-day guarantee

Nasal delivery
No needles, no pills
Hemp-derived
THCV · CBD · CBC blend
Contains no THC
Made to be non-detectable on standard workplace drug screens — check with your employer or testing provider first
Fast absorption
Non-digestive nasal delivery
The system
01.

Phase 01
Daily appetite support for the active loss phase — built to back the work you're putting in.
Save 15% with monthly auto-refill
02.

Phase 02
Daily support for the maintenance phase — the window when regain risk runs highest.
Save 15% with monthly auto-refill
80%.
regain within 5 years in long-term follow-up studies
— Wing & Phelan, 2005
⅔.
regain within 12 months of stopping injectable therapy
— Wilding et al., Diabetes Obes Metab 2022
34–46%.
intranasal bioavailability vs. 6–19% oral
— Paudel et al., Drug Dev Ind Pharm 2010 (cannabidiol)
0.
needles, sugars, or stimulant crashes
— Oprimaze formulation
“Losing the weight is the start. Keeping it off is the win.”
Two sprays. Two phases. One plan.
The position
Free guide
The GLP-1 exit plan covers the 12-month window after treatment ends — what the published research says happens, and the four-step plan for keeping your result.
Explore more
The evidence
34–46%.
Intranasal bioavailability vs. 6–19% oral
— Cannabidiol delivery research — not an Oprimaze measurement
<10 min.
Average onset for nasal cannabinoids
— Delivery-science research
0g.
Added sugar in either formula
— Oprimaze label
0.
THC — the active is THCV; made to be non-detectable on standard workplace drug screens
— Third-party tested
These figures describe published delivery science and our own product data — not Oprimaze clinical-trial results.
Phase 01 supports active loss. Phase 02 supports maintenance. Same nasal spray format — no needles, nothing to swallow.
Free shipping over $74.90 · 30-day guarantee